Влияет ли на выбор дозы ингибиторов IIb-IIIa вес пациента

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Вопрос д-ра Bonzуn д-ру Heras

- Мне очень понравилась Ваша презентация об антитромботической терапии при остром коронарном синдроме.
Мой вопрос: «Кроме подбора дозы ингибиторов IIb-IIIa в зависимости от почечной функции больного, влияет ли на выбор дозы также и вес пациента?»

С уважением,

Dr. Gustavo R. Bonzуn
Resistencia, Chaco, Argentina

 

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- Ответ д-ра Heras д-ру Bonzуn

Доза ингибиторов гликопротеина IIb/IIIa всегда подбирается в зависимости от веса больного и его почечной функции (как Вы правильно указали). На 7-слайде нашей презентации указываются дозы, в зависимости от веса пациента, это касается как болюса, так и постоянной внутривенной инфузии 3-х препаратов – абциксимаба, эптифибатида и тирофибана.
Стоит отметить, что в настоящее время появились испытания, оценивающие безопасность более высоких доз тирофибана.

Спасибо за Ваш интерес к нашей презентации. С Новым 2008 Годом!

С уважением,
Magda

Dra. Magda Heras
Cap de Secciу de Cardiologia  Clнnica
ICT
Hospital Clнnic
Villarroel, 170. 08036 Barcelona
Tel 34 93 227 9305
 Fax 34 93 451 4148
e-mail: mheras@clinic.ub.es

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